Exploring the Inflammatory and Intracellular Role of Exogenous Plasminogen Activator Inhibitor 1 (PAI-1) in Endothelial Cells

Authors

  • Arianna C. López Pérez Universidad Central del Caribe, School of Medicine Author
  • Gjina Ahmetaj Yale School of Medicine, Department of Obstetrics and Gynecology; Yale School of Medicine, Department of Physiology Author
  • Dr. McAdow Yale School of Medicine, Department of Obstetrics and Gynecology; Yale School of Medicine, Department of Physiology Author

DOI:

https://doi.org/10.71332/hnswc140

Abstract

Preeclampsia

- New onset hypertension in pregnant people

- Maternal endothelial cell dysfunction

- High maternal and fetal mortality

- PAI-1 is a biomarker

Does PAI-1 induce inflammation through eNOS mediated NFKB activation?

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Published

2025-12-22

Issue

Vol. 1 No. 2 (2025): Special Edition: Medical Student Summer Research Expo

Section

Articles

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Copyright (c) 2025 Arianna C. López Pérez, Gjina Ahmetaj, Dr. McAdow (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain copyright of their articles. All works are published under the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly cited.